Physicochemical
properties
Bootcamp
Learn how physicochemical properties are measured to design quality candidates during drug discovery
This is a can’t-miss series of live, virtual short courses for anyone looking to refresh their knowledge of the applications of physicochemical properties!
The goal of this lecture series is to provide attendees with a comprehensive overview of physicochemical properties, including how they relate to one another and how they can be measured. The original course was attended virtually by individuals from multiple organizations, however the course is also appropriate for teams within the same company.
The Presenter
Laurence Philippe-Venec
Founder
PIC Analytics
Laurence Philippe-Venec obtained her PhD in Analytical Chemistry and Separation Sciences from Pierre and Marie Curie University in Paris, France. She has over 28 years of experience in Analytical Chemistry and a Regulatory Affairs Professionals Certificate in Pharmaceuticals. She established her company, PIC Analytics, in 2018 to provide guidance for the characterization and development of drug compounds as an independent consultant.
LECTURE TOPICS
1
Lipophilicity in Drug Design
2
Separation Techniques to Measure Lipophilicity by RP-HPLC, Blood Brain barrier by IAM-HPLC, and Protein Binding by HSA-HPLC
3
Kinetic and Thermodynamic Solubility by Shake-Flask
4
pKa by Capillary Electrophoresis
5
Intramolecular Hydrogen Bond and Polarity Index by SFC
6
Study Cases
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